Organizing & Scientific Committee
Chris Reutelingsperger is Professor of Biochemistry of Apoptosis at the Cardiovascular Research Institute of Maastricht (CARIM) at Maastricht University. He was senior Research Fellow of the Royal Dutch Academy of Sciences (KNAW). Currently, he is Principal Investigator of the research theme “Vascular Aspects” of CARIM and his research interests focus on annexins in vascular inflammation and remodeling with emphasis on annexin A5. He discovered annexin A5 as a vascular anticoagulant and was the first to see the potential of annexin A5 as a molecular imaging agent to measure cell death. He (co)-authored >175 peer reviewed papers and is (co)-inventor to 10 granted patents. He is founder and Chairman of the Board of the cross-border Virtual Research Laboratory Euregional PACT in the Flanders-Netherlands Euregion. He is co-founder of 3 Biotech Companies related to annexins in Diagnosis and Therapy. He served at the Board of Directors of Immuno-Designed-Molecules and was Scientific Advisor to Theseus Imaging.
Dr Leon Schurgers is working as senior scientist at the department of biochemistry, Cardiovascular Research Institute CARIM, Maastricht University. Here he works together with Prof. Chris Reutelingsperger to elucidate the molecular mechanisms of vitamin K-dependent proteins (VKDP) by which vascular disease is initiated and propagated: key cellular events include activation and apoptosis of vascular smooth muscle cells (VSMC), and the formation of matrix vesicles and apoptotic bodies The regulation of VKDP biosynthesis, its sites of action and its putative relationship with apoptosis is insufficient to understand the pathogenesis of ectopic calcification at a level that allows the development of novel diagnostic tools and therapeutic strategies.